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first_imgIt was the “head thing” that seemed like window dressing to Madeline Meehan, the Harvard Innovation Labs operations director who wanted to lose a few pounds.In the end, she says it was the “head thing” that made her a believer.“I thought it was all about the weight, but it’s really not,” Meehan said. “It’s about screwing your head on in a different direction.”Over 16 weeks this past fall, Meehan put herself at the mercy of a Harvard Launch Lab startup, Gain Life, and found the pounds coming off. By the time the program wrapped up in February, she had lost 30 pounds.Not bad results from a casual conversation.Meehan became a Gain Life guinea pig in October while visiting the Harvard Launch Lab, a relatively new, curated, co-working space in Allston for startups founded by Harvard graduates.Meehan was walking past Sean Eldridge, a Harvard Business School graduate and one of Gain Life’s co-founders, when he called Meehan over to ask what she thought of the name PowerUp for the company’s weight-loss program for women.Next thing Meehan knew, she was enrolled in the first PowerUp cohort, engaging digitally with a coach and a group of fellow wannabe weight losers. Over the coming weeks, Meehan changed her diet and exercise habits, but also fought what Eldridge calls “the battle between the ears” — seeking an internal shift that Eldridge says is key in successful weight loss and an important element in Gain Life’s programs.Madeline Meehan discusses the PowerUp program with team members Julia Lennon (left) and Ian Richardson.The casual encounter that led Meehan to Eldridge was accidental, but not entirely by accident. The Launch Lab is designed to encourage interaction between the roughly two dozen startup companies manning 130 desks cheek-by-jowl in two large, adjoining open spaces.Not quite two years old, the Launch Lab is part of a growing culture of entrepreneurship fostered at the Harvard Innovation Lab across the street, which offer space, networking, expert advice from “entrepreneurs in residence,” and other support to student entrepreneurs.The University-wide entrepreneurial nexus is about to grow bigger, with the planned addition of the Life Lab, 15,000 square feet of laboratory space for biomedical or biotech startups, which make up a significant proportion of the startup population, Meehan said.Eldridge and Ian Richardson, who joined Gain Life in September, said the Launch Lab environment is supportive, naturally collegial, and fertile ground for a startup. The “pay-it-forward” ethos means that those starting out can seek advice from those in older companies. Gain Life, for example, can offer experience-based advice in product development and deployment, but will look to others when it comes to securing external funding, a step it has yet to take.“From an outsider’s perspective, the ecosystem that’s been built here is second to none,” said Richardson, a graduate of Furman University in South Carolina. “The idea that you can kind of have these EIRs [entrepreneurs-in-residence], these mentors, help you start something from nothing is not something you see all over the country. This is very much a unique thing.“It has accelerated … my own learning in a way I never thought possible. I didn’t know, seven months in, I would have such a strong grasp of ‘Hey, this is how funding works, this is how product development works, this is how marketing works.’ It’s just an amazing resource.”Gain Life is seeking a foothold in a marketplace crowded with fad diets, diet books, weight-loss programs, and not a few wild claims of success. Eldridge thinks he and co-founder John Peters — a nutrition expert he met while working at Procter & Gamble after leaving HBS — have found something that both sets the company apart and works for most of their clients.Peters’ research into people who had lost a lot of weight and kept it off — an average of 70 pounds for six years — revealed the importance of the mental component, Eldridge said. Though there were practices in common — such as exercising for 150 minutes a week — what was most important was an identity change: They recognized their post-weight-loss selves as different people, and had developed a new mindset about themselves, food, and exercise.Gain Life’s programs, Eldridge said, draw on that work — as well as practices gleaned from cognitive behavioral therapy and self-determination theory — to help people achieve a similar change.“You have to blog every day,” Meehan said of her own experience, “and at first I wasn’t blogging every day because you have to write how you feel. And I thought again, ‘Is this crazy? But I’ll do it because I like these guys.’ I was doing it more to help the startup and then the more I got into it I was like, ‘Wow, this is working.’”The company recently concluded an 18-month research-and-development phase that tested their programs tailored to men and women. The 16-week programs begin with an in-depth consultation with a coach who probes the deeper reasons behind the desire for weight loss, Eldridge said. The answers inform both coach and client and help align the program’s goals to the client’s broader life aims.For example, Eldridge said, a middle-aged man may want to lose 40 pounds and, when asked why, he might say to look better and get back into shape. Asked why he wants to get back into shape, he might reveal that he wants to be alive for his young daughter’s wedding day. When asked why the wedding is important, he might respond that his own father developed diabetes, and, when asked about that, he might reveal that the diabetes began a cascade of health ills and, ultimately, he doesn’t want his own poor health to be a burden on his children.Of those who’ve gone through the programs, 80 to 85 percent complete the course, according to company statistics. After a year, men lost an average of 14 percent of body weight and women 12 percent, both better than the 5 percent Richardson said is considered the industry “gold standard.”The company is looking to expand in the next year and is targeting both the consumer and corporate markets, Eldridge said. He wants the number of clients to grow to 10,000 and expects the 25-person staff — most of whom are coaches who work from various locations — to more than double.That means the company will be embarking on a personnel search, but it doesn’t mean it’s quite ready to leave the friendly confines of the Launch Lab, with its easy access to i-lab resources, professors with whom Eldridge studied as a student, and even the restaurants he visited then.“It definitely makes me feel like I’m more tied to the University … because it’s continuing to give so much to me,” Eldridge said. “We’re in no rush to get out of here.”last_img read more

first_img July 1, 2006 Regular News Civil Legal Assistance Act cleared to go statewide Civil Legal Assistance Act cleared to go statewidecenter_img Jan Pudlow Senior Editor Now that The Florida Bar Foundation has the governor’s blessing, they will take the Florida Access to Civil Legal Assistance Act statewide.As soon as Gov. Jeb Bush approved $2.5 million, the largest appropriation from the state ever, that was the Foundation’s plan. There was excitement to expand the program from the seven-circuit pilot to all 20 circuits. But that excitement was short-lived.Soon thereafter, the statewide goal was put on hold, because of promises made between Rep. Dudley Goodlette, R-Naples, and the governor’s general counsel, Raquel Rodriguez.As Terry Russell, the former 2001-02 Bar president who created the first plan to get state government to pitch in to help poor people with civil legal problems, said: “We want to make sure the Foundation’s credibility and willingness to work with the governor is maintained and protected and preserved.”Goodlette explained the chronology of events:Last year, Bush vetoed the $5 million for the program three weeks after legislators voted for it.“The governor told me at the time that the motivating factor in choosing to veto was he simply was reluctant to expand government,” Goodlette said. “He wanted to gain more comfort with the success of the pilot program before he was prepared to spend more money and make it a larger program.”This year, Goodlette helped achieve the $2.5 million appropriation.“What I learned from the Foundation is with $2.5 million, the program could be expanded,” Goodlette said. “I discussed that with Rocky Rodriguez, and she thought if that were the case, the governor would have an outlook on it similar to last year, that that was growing government.”At that point, Goodlette said, “I assured her that if that was the governor’s view, assuming he would not veto the $2.5 million, it would remain a pilot program in seven circuits.”Five weeks ago, Goodlette said, Rodriguez “indicated to me, based upon her conversations with the governor, that she thought it would be better if it remained a pilot program. She would urge him to sign the bill.”Once Goodlette learned the Foundation did want to go statewide, he got back to Rodriguez and said: “I want to be straight up with you. The Foundation has said they can expand it statewide.”But he wanted to keep his word about keeping it limited to the pilot. The second week of June, Goodlette said, Rodriguez told him she had talked to the governor and he said go ahead and take it statewide if that was important to Goodlette and the Bar.“I couldn’t be more pleased,” Goodlette said.The Foundation anticipates making grants in each of the 20 judical circuits within the next two months, subject to entering into a contract with the Department of Community Affairs. Interested legal aid programs should contact Camille Stawicki, grant coordinator at the Foundation, at 800-541-2195 or [email protected]last_img read more

first_imgDec 14, 2004 (CIDRAP News) – As part of efforts to improve the nation’s long-term supply of influenza vaccine, the federal government is launching a clinical trial to help get a German-made vaccine licensed for regular use in the United States.The Department of Health and Human Services (HHS) announced Dec 7 it would buy 1.2 million doses of the Fluarix vaccine made by GlaxoSmithKline (GSK) Biologicals to help ease the shortage. The vaccine is used in 70 countries, but because it is not licensed in the United States, people will have to sign a form acknowledging possible risks before they receive it.Two days after that announcement, federal officials announced plans to recruit 1,000 healthy adults for a clinical trial of the vaccine at four sites. The National Institute of Allergy and Infectious Diseases (NIAID) is collaborating with GSK Biologicals, based in Rixensart, Belgium, on the trial.Dr. Pamela McInnes, deputy director of the NIAID’s Division of Microbiology and Infectious Diseases, said the trial was prompted by the US flu vaccine shortage, which arose when contamination problems forced Chiron Corp. to cancel its shipment of 48 million doses in October. “We’re doing whatever we can to secure the vaccine supply for the next season,” McInnes told CIDRAP NewsMcInnes said the NIAID is funding the clinical components of the trial, such as recruiting volunteers and administering the vaccine, while GSK will cover some infrastructure costs and the testing of blood samples to assess the immune response. She said she couldn’t estimate the cost of the trial at this point.The trial will be conducted by four NIAID-supported Vaccine and Treatment Evaluation Units, at the University of Rochester Medical Center, Cincinnati Children’s Hospital, the University of Maryland School of Medicine in Baltimore, and Baylor College of Medicine in Houston.In the NIAID announcement, lead investigator John Treanor, MD, of the University of Rochester, said, “Although the vaccine we are testing has a very long safety record in Europe and other parts of the world, the type of study we are conducting must be done before the vaccine can be licensed for use in the United States.”Four of every five participants in the trial will receive Fluarix, while the fifth will receive a placebo, the NIAID said. Those receiving the placebo will be offered US-licensed vaccine at the end of the month-long study.When HHS announced its plan to buy GSK vaccine last week, the company said it had long-term plans to seek a US license for the product. A Dec 9 Washington Post report quoted the company as saying it intends to sell 10 million to 20 million doses in the United States for next year’s flu season if it gets a license.In other recent flu-vaccine developments, the United Kingdom’s drug regulatory agency said last week it was extending the license suspension for Chiron’s Liverpool vaccine plant for another 3 months. The Medicines and Healthcare Products Regulatory Agency (MHRA) suspended the plant’s license because of contamination problems Oct 5, forcing cancellation of the company’s vaccine shipments to the United States.”This new suspension does not result from any newly identified safety issues or findings at the Liverpool plant,” the MHRA said. “It is routine regulatory action to give Chiron more time to carry out the extensive and detailed remedial plan which is now being put in place.”The MHRA said it was keeping the US Food and Drug Administration (FDA) well informed of developments and would include FDA inspectors on an upcoming visit to check Chiron’s progress in fixing problems at the plant. The FDA has come under fire for not predicting Chiron’s problems and reacting to them sooner.”The suspension can be lifted at any time if Chiron is able to satisfy the MHRA that it has rectified the site’s problems,” the MHRA statement added.Also last week, Chiron announced it had received an FDA warning letter asking for more information about the company’s investigations of problems at the Liverpool plant. The letter, stemming from a remediation plan the company submitted in November, asks for more details about investigations into “current Good manufacturing Practices deviations” and related studies.The FDA gave Chiron 15 working days to respond to the letter, the company said.See also:Dec 9 NIAID news releaselast_img read more

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first_imgR-Pharm said it received approval for Coronavir after Phase III clinical trials involving 168 patients with COVID-19.The drug was first approved for in-hospital use to treat COVID-19 in July, a government register showed.Coronavir’s trial was comparatively small. The European health regulator on Friday endorsed the use of the steroid dexamethasone in the treatment of COVID-19 patients after a study by UK researchers on several thousand patients.R-Pharm has started talks with pharmacies about orders, the company’s spokeswoman said, with Coronavir supplies expected to be rolled out in the near future, possibly as soon as next week.Coronavir is made at R-Pharm’s facility in Yaroslavl, about 300 km (186 miles) northeast of Moscow.Avifavir has been available in hospitals since June but has yet to be supplied to pharmacies.  Russia has approved R-Pharm’s Coronavir treatment for outpatients with mild to moderate COVID-19 infections and the antiviral drug could be rolled out to pharmacies in the country as soon as next week, the company said on Friday.Coronavir’s approval as a prescription drug follows the green light for another Russian COVID-19 drug, Avifavir, in May. Both are based on favipiravir, which was developed in Japan and is widely used as the basis for viral treatments.R-Pharm’s announcement is another sign Russia is pushing hard to take a global lead in the race against the virus. It is already exporting its COVID-19 tests and has clinched several international deals for supplies of its Sputnik-V vaccine. Topics :last_img read more

first_imgMore: FootballRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starChelsea defender Fikayo Tomori reveals why he made U-turn over transfer deadline day moveMikel Arteta rates Thomas Partey’s chances of making his Arsenal debut vs Man CityBut Sarri has questioned the timing of the fixture, which takes place on Wednesday evening at the Gillette Stadium in Massachusetts, and has suggested that the game interrupts his side’s preparation for the Europa League final against Arsenal on May 29.Sarri, meanwhile, admitted after Chelsea’s goalless draw with Leicester City on Sunday that he is uncertain about his future, despite meeting the club’s season target of securing a Champions League place.Asked if he will be at Stamford Bridge next season, Sarri replied: ‘I think so, but I am not sure.‘I can say only that the club asked me for the Champions League, and we reached the target.‘As you know very well, I love English football. I love the Premier League; it’s fantastic and the level is the best in the world, I think. The atmosphere in the stadiums is wonderful. I would like very much to stay here.’More: Arsenal FCArsenal flop Denis Suarez delivers verdict on Thomas Partey and Lucas Torreira movesThomas Partey debut? Ian Wright picks his Arsenal starting XI vs Manchester CityArsene Wenger explains why Mikel Arteta is ‘lucky’ to be managing Arsenal Comment Advertisement Metro Sport ReporterWednesday 15 May 2019 9:51 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link86Shares SARRI’S RECORD AT CHELSEA GAMES: 62WINS: 38DRAWS: 13DEFEATS: 11WIN RATIO: 61.2% Roman Abramovich ready to sack Maurizio Sarri after Chelsea’s Europa League final Chelsea fans have not warmed to Sarri’s tactics at Stamford Bridge (Getty Images)During several Chelsea matches this season, Sarri’s decisions regarding substitutions have been booed, while fans chanted ‘f*** Sarri-ball’ during the team’s 2-1 win away to Cardiff City on March 31.It’s also claimed that Sarri is ‘not loved’ by Ambramovich and the Italian’s decision to openly criticise the club’s post-season friendly against New England Revolution in the United States has not gone down well with Chelsea’s hierarchy.Abramovich played an integral role in setting up the friendly with New England Revolution owner Robert Kraft with the proceeds of the match going towards 15 organisations that tackle antisemitism. Advertisement Maurizio Sarri’s time at Chelsea could be up in a few weeks (PA Wire)Roman Abramovich is ready to sack Maurizio Sarri after Chelsea’s Europa League final against Arsenal, according to reports in Italy.In his first season in England, Sarri guided Chelsea to third in the Premier League but after losing to Manchester City in the Carabao Cup final, the Italian still has the chance to win silverware if his side beat Arsenal in Baku on May 29.Sarri will still have two years left on his contract with Chelsea this summer after joining from Napoli last year.But according to Gazzetta dello Sport, Roman Ambramovich is ready cut short the 60-year-old’s time at Stamford Bridge.AdvertisementAdvertisementADVERTISEMENTThe report claims that Abramovich’s decision is not based on Chelsea’s achievements this season but are centered around Sarri’s poor relationship with the club’s fans.last_img read more

first_imgThe offer of large lots and big sheds has proven too good to refuse for buyers of Townsville’s newest residential community, The Orchard.THE offer of large lots and big sheds has proven too good to refuse for buyers of Townsville’s newest residential community, The Orchard.The developer launched a free 6x6m shed campaign with every new homesite sold before June 30 and has been inundated with inquiry.The Orchard’s Sales and Marketing Director Pene Slogrove said that questions about sheds were the most common from potential buyers.“From past experience we know that the shed is a big part of the decision making process for buyers — particularly on larger-lot communities like The Orchard,” Mrs Slogrove said.“It is often one of the first questions we get. People want to know what size they are able to have and where they can put it.“Fortunately, the size of the lots at The Orchard means we can be very flexible with our building guidelines around where and how large a shed can be.More from news01:21Buyer demand explodes in Townsville’s 2019 flood-affected suburbs12 Sep 202001:21‘Giant surge’ in new home sales lifts Townsville property market10 Sep 2020“Residents can choose to use their sheds for their cars and save money on having to build a carport as part of their house.“The free shed offer means all they have to do is decide where they will put it and what they will use it for.”In just a few weeks, the free shed offer has delivered a number of sales and substantial inquiry for the developer. Kent Village is the first stage release for The Orchard and offers new homesites from 1,000 to 2,400sq m.The Orchard is located off Darling Road in Jensen and is fully serviced including town water and sewage connection and NBN ready. Unlike other large- lot developments, The Orchard also boasts kurb and channelling meaning a better aesthetic as well as improved storm water run-off.Buyers are encouraged to register their interest at or call Penelope Slogrove on 0439 749 700.last_img read more

first_imgNZ Herald 20 Sep 2011A pregnant teenager says sex education in schools does not prevent young people from having sex – if anything, it encourages it. Amber-Leigh Erasmus is due to give birth to her first child on Saturday, a result of having unprotected sex during New Year celebrations. The Hibiscus Coast 17-year-old lost her virginity at 14, a year after she was taught about sex at school and the fact it was “okay as long as you consented”. Amber-Leigh said she was brought up with the idea that you should wait until marriage before having sex. But the things she learned at school made sex seem like a perfectly normal thing to do, so she tried it, using the free flavoured condoms she had been given in class. “It accustomed me to absolutely everything and it became a normality to me.” Now she is questioning why students are being taught about sex when they are so young, especially given sex isn’t legal until the age of 16. read more

first_imgAlready on a 232-years’ in prison sentence and six life terms, 25 year-old Mpho Rakgwale now awaits sentencing on November 30 for new convictions.Rakgwale is South Africa’s, and potentially Africa’s youngest convicted serial rapist.Rakgwale was back in the high court in Johannesburg on Wednesday after being found guilty of rape, kidnapping and robbery last year.He was convicted for a mind-boggling 61 charges, with 21 of those being for rape while 17 were for kidnapping and six for the illegal possession of firearms.Rakgwale was slapped with further five charges for aggravated robbery, six for the illegal possession of ammunition and another six for robbery.On Wednesday, the South African was convicted on 12 more charged for several kidnappings, rapes and robberies between May and September 2012.Judge AJ Sithole summed up the victims’ testimonies with revelations some teenage victims were raped in a Johannesburg cemetery.According to the court, some of his victims were his childhood friends.last_img read more

first_imgLocalNews US Presidential candidate allegedly linked to 1981 failed coup attempt in Dominica by: – January 21, 2012 Sharing is caring! 94 Views   no discussions Tweet Sharecenter_img Share Ron Paul. Photo credit: Newsone.comIn 1981, a lawyer tried to subpoena Ron Paul to testify in the trial of Don Black, a Grand Wizard for the Ku Klux Klan who would later go on to found the white supremacist, neo-Nazi website, Stormfront. Black was charged along with two other Klansmen with planning to violently overthrow the small Caribbean country of Dominica in what they called “Operation Red Dog.” While a judge refused to subpoena Paul, Don Black would come back to haunt him many years later.In 1981 a group of American and Canadian white supremacists lead by Klansman and mercenary, Michael (Mike) Perdue planned on taking over a small West Indian country called Dominica by overthrowing the government and Prime Minister Eugenia Charles and restoring its previous prime minister, Patrick Johns into power. The group planned to create an Aryan paradise in Dominica and make money through casinos, cocaine and brothels.On the day the group of white supremacists were supposed to travel to Dominica, they were arrested by ATF agents and were found with over thirty automatic weapons, shotguns, rifles, handguns, dynamite, ammunition, a confederate flag and a Nazi flag. The plan would be dubbed “The Bayou Of Pigs” after the failed invasion of Cuba.The leader of the group, Michael Perdue, would plead guilty to planning the coup and turned state’s evidence. Perdue would testify that several other people helped organize and fund the coup and that two Texas politicians were aware of the plan. Among those Perdue implicated were infamous white supremacist, David Duke, former Texas Governor, John Connally and Congressman, Ron Paul whom he claimed knew about the plot. Connally was credited with helping Paul win his first congressional election.A judge refused to subpoena Paul and Connally despite the fact that Perdue had claimed that both of them were aware of the plot. Don Black’s friend and fellow KKK Grand Wizard, David Duke was called to testify before a grand jury but claimed that he would take the Fifth Amendment and never testified. While Duke was never charged with a crime, several books points to Duke as the organizer who connected Perdue to the other mercenary Klansmen and the people who funded their endeavor. (1 2 3) Everyone else implicated by Perdue was charged with the plot.Perdue implicated three men as funders of the plot, L.E. Matthews of Jackson, Mississippi, James C. White of Houston, and David Duke’s close friend and backer, J.W. Kirkpatrick. Kirpatrick would kill himself before he could stand trial and White and Matthews would be acquitted in court. Former Prime Minister of Dominica, Patrick Johns would be sentenced to 12 years in prison for his part of the plot. Michael Perdue, Don Black and seven other Klansmen would be sentenced to only 3 years in prison.Ron Paul has never made a statement denying knowledge of the plot despite the fact that he was implicated by Perdue and almost subpoenaed. Two of the people involved in the plot, Don Black and David Duke have gone on to become two of the most prominent white supremacists of the modern era, and also two of Paul’s most controversial supporters.Paul would be once again tied to Don Black 26 years after the Bayou Of Pigs. After it was revealed that Black donated $500 dollars to the Ron Paul Presidential campaign, Ron Paul’s campaign refused to give it back. Paul was photographed with Black and his son by David Duke’s former assistant, Jamie Kelso who was an organizer for Ron Paul and the owner of white supremacist sites, and and a moderator for Black’s neo-Nazi website, Stormfront.Black would become one of Paul’s most enthusiastic supporters and helped rally the white supremacist community around Paul, through Stormfront. Paul would praise another Operation Red Dog planner, David Duke in his newsletters and Duke would return the favor calling him “our king” and endorsing him for President.This would not be the first time Paul was tied to white supremacists. In 80s, Paul claimed that the best source of his campaign donations came from a list from notorious neo-Nazi, Willis Carto’s publication, The Spotlight. In the 90s, Paul’s newsletters were originally discovered from an online neo-Nazi directory. As recently as 2006, Paul was scheduled to appear on David Duke’s white supremacist protégé, James Edwards’ radio show, “The Political Cesspool.”Given the scrutiny given to presidential candidates, shouldn’t Paul’s connection to an attempted violent invasion of a small island by white supremacists be re-investigated. If the media investigates every accusation of affairs or sexual harassment for Herman Cain or Newt Gingrich, shouldn’t they investigate accusations that Paul knew about a white supremacist plot to violently overthrow the government of a small Black island, especially with Paul’s other connections to white supremacists?Written by Casey Gane-McCalla, Lead Sharelast_img read more